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The present study found that with the increase in the degree of ferroptosis, renal function in the rat model of urolithiasis was significantly reduced, and the number of TUNEL-positive cells in renal tissues was notably increased

Scott KP, Grimaldi R, Cunningham M, et al

found that dexamethasone decreased GSH expression by upregulating DPEP-1, thereby increasing the sensitivity of PTEC to ferroptosis [37]

GLS overexpression has been observed in different tumor cells, and these enzymes are found to function in the metabolic reprogramming of glutamine addiction in cancer 198