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Carnosine scavenges lipid peroxidation-derived aldehydes (e.g., 4-hydroxynonenal (HNE) and malondialdehyde (MDA)), reducing EC damage and inhibiting early atherosclerotic lesion formation in ApoE-null mice by 34% and reduced aldehyde-protein adducts in lesions [180]

The present review synthesizes current literature on the folate-MTHFR-SAM axis as a modulator of epigenetic stability in autoimmune disease

SLC7A11 functions in a variety of roles in cancer including metabolic reprogramming, nutrient dependency, growth, proliferation, invasion, and drug resistance ( Figure 1 )

and ZYX, YBH and YML finalized the manuscript

doi: 10.1093/jn/127.11.2135