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However, the duration of analgesia was longer for dermorphin than for [D-Arg]dermorphin when each was given at its maximally effective dose

Missing doses disrupts peptide levels and slows results

These factors may include age, ethnicity, pregnancy, use of certain medications, individual genetic variation, the assay method and any measurement errors associated with its use

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Pickart & Margolina, Int J Mol Sci, 2018 Why it matters A peptide the body already makes