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Future consideration Taking in account the scientific evidence summarized in this review, NP is a complex network of several molecular processes, including nitro-oxidative stress, immune response, and TRP channels activation, among others

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After fixation of the biopsy specimens, free floating 50-m-thick sections were cut and stained by using rabbit anti-protein gene product 9.5 antibody (Dako Netherlands BV, Eindhoven, the Netherlands) and visualized using a goat anti-rabbit Alexa fluor 488 antibody (Invitrogen,/Life Technologies, Carlsbad, CA, USA)

doi: 10.3390/ijms20153673 97 DorscheidDGauvreauGMGeorasSNHiemstraPSVarricchiGLambrechtBNet al

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In the majority of these studies, maternal toxicity was not evaluated