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Hence, a proper understanding of these factors helps establish optimal storage conditions for preserving the integrity of LNPs and their loads, ensuring that therapeutic efficacy is maintained throughout their shelf life

In an early phase 1 study of healthy obese participants, setmelanotide demonstrated significant weight loss compared to baseline for all treatment groups receiving 0.01 mg/kg/24 h via SC infusion (NCT02431442) ( Table 2 )

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