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doi: 10.3389/fphar.2025.1712869 Received 25 September 2025 Revised 13 December 2025 Accepted 17 December 2025 Published 07 January 2026 Volume 16 - 2025 Edited by Hua Chen, Ningxia Medical University, China Reviewed by Wenlong Sun, Shandong University of Technology, China Masanori Tamaki, Tokushima University, Japan Updates Copyright 2026 Ji, Li, Fang and Li