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Extracellular DNAa danger signal triggering immunothrombosis

Overall, studying lipid peroxidation, xCT/GPX 4 activity, and redox metabolites will be key to confirming on-target ferroptosis involvement in the promising outcomes of these trials

In addition, there is a likely analogy (see for review i.e., (Seiwerth et al., 2018)) with the attenuated fibrosis and scar formation in other tissues (i.e., the skin, muscle, tendon, and ligament) (Mikus et al., 2001

This means we now have a window into the Parkinsons brain - allowing us to study these precious cells at close quarters, work out why they stop working and die, and testing new ideas and treatments