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Description
ERK1/2 functions to enhance mitogenic signals in cells and can be activated by elevated intracellular calcium (from PLC/PKC events), and indirectly via PKA, both of which as outlined are stimulated by GH and IGF activity (106, 124)
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Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma
R.GaleaJ.et al (2016)
Maczurek A, Hager K, Kenklies M, Sharman M, Martins R, Engel J, Carlson DA, Mnch G
Mol Cell Biol (2002) 22(6):183443
