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Epithalon Amidate: C-Terminal Protection Epithalon amidate is the same Ala-Glu-Asp-Gly sequence with a single chemical change: the carboxyl group (-COOH) at the C-terminus is replaced with an amide group (-CONH2)

4 (2011): 12071229, 10.1111/J.1476-5381.2010.01163.X

IIAEK targets intestinal alkaline phosphatase (IAP) to improve cholesterol metabolism with a specific activation of IAP and downregulation of ABCA1

Because cells have a high-Km glucose transporter 2 (Glut2) and high-Km glucokinase, they can respond to elevated levels of blood glucose, which is known as supply-driven metabolism [31, 32]

The tag consists of six or more histidine residues positioned at either N or C terminus of a recombinant protein

Then, the deparaffinized sections were treated with proteinase K for 30 min at 37 C and rinsed in PBS