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Except for ELIXA and EXSCEL [56, 59], all other major CVOTs point towards cardiovascular benefits of GLP-1RAs [53, 54, 61, 63, 66,67,68]

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In terms of lowering HbA1c, dulaglutide, when administered once a week, was demonstrated to be more effective than exenatide twice a day, by 1.51% vs.0.99% [94]

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10.1053/j.gastro.2007.03.054 6 BaylissW
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