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Specifically, AMPK activation promotes TFE3 nuclear translocation, which enhances the transcription of autophagy genes, reduces ROS accumulation, and alleviates ERS

Markers like 8-OHdG, 8-iso-PGF2, and dityrosine provide a snapshot of the oxidative damage that may be driving neuroinflammation and immune dysfunction

van der Zee, J

Available from: pmid:14641075 16

Pentose phosphate pathway protects E

This review summarizes five decades of TOR/mTOR research (hereafter referred to as mTOR unless describing the work in yeast or Drosophila), covering molecular mechanisms and highlighting recent successes in targeting components of the mTOR pathway in clinical trials