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Beagles supplemented for two months with L-carnitine and alpha-lipoic acid showed improved learning and discrimination compared with beagles that received no supplement

In patients with pre-existing seizure activity, an increase in seizure frequency and/or severity has been reported

Accessed 20 Apr 2017 Stanley CA, Bennett MJ, Longo N (2014) Plasma membrane carnitine transporter defect, In: Valle D, Beaudet AL, Vogelstein B, Kinzler KW, Antonarakis SE, Ballabio A, Gibson K, Mitchell G (eds) The online metabolic and molecular bases of inherited disease New York, McGraw-Hill, New York

These molecules feed into the citric acid cycle and the electron transport chain, driving ATP synthesis

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In a study of overweight women with polycystic ovary syndrome, carnitine supplements lowered glucose and insulin blood levels and reduced insulin resistance [29]