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Lower than 5 mg/mL requires large injection volumes, which can be uncomfortable

When there is too much glucagon, the chances of high blood glucose levels are increased

Contraindications include personal or family history of medullary thyroid carcinoma, MEN-2, prior severe hypersensitivity to GLP-1s, history of pancreatitis, severe gastroparesis, and pregnancy or breastfeeding

Do not touch the cleaned surface

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Nonetheless, although many experimental and clinical findings indicate that DPP-4 plays a role in the pathogenesis of autoimmune diseases, DPP-4 inhibition has controversial effects in autoimmune or inflammatory diseases, which might be related to the ubiquitous tissue distribution and tissue-specific regulation of DPP-4/CD26, as well as to the numerous functions and effects of DPP-4/CD26 [46]