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Moreover, emerging research suggests that GlyT1 inhibition plays a role in preserving vascular integrity in ischemic conditions

2.2 Iron overload in the brain In contrast to iron deficiency, excess iron in the brain is neurotoxic due to its ability to produce reactive oxygen species (ROS) and resultant oxidative stress (Salvador et al., 2010)
[DOI] [PMC free article] [PubMed] [Google Scholar] 78.Nagarkoti S., Dubey M., Sadaf S., Awasthi D., Chandra T., Jagavelu K., Kumar S., Dikshit M

doi: 10.1016/j.toxicon.2020.08.031

[DOI] [PubMed] [Google Scholar] 155.Jeong W.I., Osei-Hyiaman D., Park O., Liu J., Btkai S., Mukhopadhyay P., Horiguchi N., Harvey-White J., Marsicano G., Lutz B., et al