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We previously showed that IGF-1Rs are overexpressed in primary prostate cancer (PCa) and are further upregulated on progression to androgen-independent metastatic disease 2,3

When compared to control thresholds, which have a baseline of 1.31mIU/l or 0.4ng/ml, this increase might represent more than a 60-fold enhancement

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[DOI] [PMC free article] [PubMed] [Google Scholar] 195.Adil M., Amin S.S., Mohtashim M

Singhal P, Nigam V, Vidyarthi A

Currently, GnRH agonists are approved by FDA to be used in the preoperative treatment of UF