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Angiogenesis: Stimulates blood vessel growth and tissue repair, including in aged animals (PubMed 15037013)

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Conclusion While oral B12 supplements can be beneficial, B12 shots offer several advantages especially for those who have trouble absorbing B12 through their digestive system

Smaller volumes mean less liquid under the skin per injection, which generally means less discomfort and less chance of injection site irritation

Particularly useful if reflux has already caused some esophageal irritation