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[2] The decline of GH results in reduced production of insulin-like growth factor (IGF-1), which typically works in tandem to manage and modulate our fat, protein, and glucose metabolism

7.4.1 Targeted epigenetic interventions 7.4.1.1 Small-molecule epigenetic modulators Small-molecule epigenetic modulators, including DNA methyltransferase inhibitors and histone deacetylase inhibitors, may restore normal DNA methylation and histone acetylation patterns in individuals affected by EED exposure (145)

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