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doi: 10.1080/02640414.2013.797098
KesslerIcekson et al
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The T1DM meta-analysis was dominated primarily by the Diabetes Control and Complications Trial (DCCT), which accounted for 1,186 of the 1,228 patients in the meta-analysis 16 and demonstrated an annualized risk difference of 1.84 (95% CI 2.56 to 1.11) in favour of enhanced glycaemic control 160
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The gene product, ALDH2, localises to the mitochondria where it catalyses the detoxification of aldehydes
