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Three repeats were set for each group

NAC can cross the blood-brain barrier and mitigate age-associated memory decline (117,120)

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In addition, we assessed the effect of sulfasalazine in unilateral ureteral obstruction (UUO) model, another established model of the formation of TLS in the kidney (Supplemental Figure 9A)

Mechanistically, drugs such as mecamylamine act as noncompetitive antagonists at neuronal nicotinic acetylcholine receptors, producing a poretrapping block by entering and becoming trapped within the open ion channel (second panel)