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Thus, direct NAD + administration may exhibit unique effects compared to NAD + precursors and modulators, warranting further investigation, especially given the rise of wellness and anti-aging clinics offering intravenous NAD + therapy, while clinical evidence is still scarce 119

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Interestingly, phosphocreatine was not detected in the plasma of both Phase-I and Phase II HSB (Table 1), indicating that the muscle and other tissues of the fish do not release phosphocreatine

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