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nevertheless, a recent study has reported that this enzyme could be considered as an independent prognostic factor in colorectal cancer patients 52

15,16 REM sleep concludes with a return to N1, sometimes with a brief period of wakefulness prior to the next sleep cycle

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In placebo-controlled clinical trials of acute mania, patients were dosed to a clinical response with a trough plasma concentration between 50 and 125 mcg/mL
