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However, the transition from preclinical findings to clinical applications poses challenges, including the need for rigorous validation of these biomarkers in diverse patient populations and the development of effective delivery systems for therapeutic agents targeting these molecules (68)

Biorheology 56, 131149

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Neurotrophic signaling deficiency exacerbates environmental risks for Alzheimers disease pathogenesis

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If you take these long term, it is worth checking your B12 status, and injections may be recommended if a deficiency is found