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Dermatopathol Basel Switz 2021

One class of molecules under consideration are activators of sGC.[66] The first molecule of this class that was studied for the treatment of ED is YC-1, a compound originally identified as an inhibitor of platelet aggregation.[67] In in-vivo experiments in rats, peak ICP after electrical stimulation of the cavernous nerves was significantly higher in animals treated with YC-1 than in animals treated with vehicle.[68] Administration of NOS-inhibitor L-NAME did not impair the erectile response after treatment with YC-1, indicating that the mechanism of action this drug is not NO-dependent.[68,69] However, the compound has been shown to enhance the sensitivity of sGC to NO

A diagnosis of cutaneous melanoma with oral metastases was confirmed on the basis of the clinical, dermoscopic, and histological data

Acta Neurobiol Exp 2024;84(Suppl.):Poster Session III, CXXXVII

Teens and young adults are most vulnerable since they have greasy skin

8 (1), e010606