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The rationale is that BPC-157 is absorbed into the bloodstream and circulates throughout the body, exerting its effects systemically

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Smart 2006)

They display structural features close to the classical neuropeptides

Later work demonstrated that the combined absence of the p53 target genes encoding the pro-apoptotic BH3-only proteins PUMA and NOXA (and to a lesser extent loss of PUMA alone) rendered lymphoid cells as resistant to DNA damage-inducing agents as loss of p53 itself [8, 9, 22]