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As the glucose is excreted there is a concomitant loss of water to maintain normal osmolarity of the urine
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21, 15071514.10.1016/j.cub.2011.07.042 61 LemireB
Our model also accounts for the efficacy of commonly-used treatments of CVS, including mitochondrial-targeted therapies, propranolol (beta blockade interferes with catecholamine-induced release of calcium via the RYR2 calcium channel (101), and amitriptyline (used for peripheral neuropathy)
