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The rGSH (reduced GSH) was obtained by subtracting GSSG (oxidizedGSH) from the total GSH

Copper can also oxidize Tau, forming intramolecular disulfide bridges via binding to the C291 and C322 on the R2 and R3 sequences, promoting both Tau phosphorylation and aggregation and also being detected in NFTs (Zubi et al., 2020)

The MTHFR 677TT genotype has been associated with increased ASD risk, potentially through impaired methylation capacity, elevated homocysteine, and altered neurodevelopmental signaling

This included a combination of oral and topical medications, targeted medical peels, and laser depigmentation sessions