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5-Amino-1MQ is a synthetic small molecule that acts as a selective inhibitor of nicotinamide N-methyltransferase (NNMT)
Using the clinical trial escalation protocol (2mg starting dose with 2mg increases every 4 weeks), reaching the 12mg maintenance dose takes approximately 20 weeks

However, traditional anti-inflammatory and analgesic therapies have substantially more extensive safety and efficacy data derived from large-scale clinical trials and long-term clinical experience

"JEFF BRIDGES Slow Magic, 1977-1978"

DSS-induced experimental colitis models