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Neurons in the substantia nigra pars compacta produce dopamine, a neurotransmitter (chemical messenger) that transmits signals from the substantia nigra to other parts of the brain
PMID 2407068
# group 2 vs group 4
In severe cases that do not respond to first-line approaches, external therapies that modulate nerve function and more invasive treatments such as medications, deep brain stimulation, and cochlear implants may be considered

doi: 10.1002/(SICI)1097-4547(20000501)60:3 3.0.CO;2-T
