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For mild pigmentation, Niacinamide or Alpha-Arbutin are gentler and ideal for daily use
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10.1089/ars.2012.5149 191 MiyajiY.YoshimuraS.SakaiN.YamagamiH.EgashiraY.ShirakawaM.et al (2015)

Intravenous (IV) infusions are one method

This makes degradation undetectable without functional assaysmass spectrometry alone won't catch it
