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Despite these benefits, pirfenidone is associated with adverse events such as gastrointestinal intolerance and skin reactions, which are typically mild to moderate and often reversible upon dose adjustment (King et al., 2014

(PubMed) Kim HJ, Chang WK, Kim MK, Lee SS, Choi BY

Bansil S, Prakash N, Kaye J, Wrigley S, Manata C, Stevens-Haas C, et al

There also has been evidence that statins may help with brain function in people with dementia, for example

This finding stems from the lack of significant differences in blood lactate concentrations between fasting and physiologically fed conditions
