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Hence, changes in intra-portal insulin levels need to be taken into consideration to correctly interpret the alterations in the GH/IGF-I axis in healthy and disease states as this helps the clinician in formulating the decision-making process of when and how to perform appropriate diagnostic work-up and whether to offer treatment to improve any accompanying metabolic consequences

Physicians should prefer lower concentrations and consider alternatives or formulations with reduced toxicity for sensitive applications such as eye drops

Nishinaga et al, 1993

Imaging robust microglial activation after lipopolysaccharide administration in humans with PET

10.1093/jn/138.10.2003S [DOI] [PubMed] [Google Scholar] Wentzel A

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