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Description
Catalases (CAT) [EC 1.11.1.6] Overview Catalases are tetrameric heme-containing enzymes that convert hydrogen peroxide to water and oxygen and are mostly found in peroxisomes (Srivalli et al., 2003)

Acknowledgements The authors thank Simone Gasper and Juliane Rdiger for expert technical assistance

Intrinsic ROS is mostly produced in cell constituents such as the cytosol, nucleus, peroxisomes, mitochondria, and endoplasmic reticulum

Recent data suggest that mTORC-2 activation through IIS relies on a putative PI3K that is insensitive to the negative feed back loop that controls activation of mTORC-1 [8]

An example of an integrative therapy would be a chemo drug called cisplatin and an antioxidant called curcumin

preclinical, not a treatment for any condition
