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One study found as many as 30% of patients hospitalized for depression were deficient in vitamin B 12 (96)
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It should be noted, however, that these are few and preliminary studies that, on the one hand, provide valuable and promising data, but on the other hand, the results are limited and have not yet been sufficiently confirmed
52 Vitamin B12 (cobalamin) and folate (vitamin B9) are critical for the synthesis of S-adenosylmethionine (SAMe)
Among the identified sites, H3K18la is the best characterized, promoting the transcription of tissue-repair and anti-inflammatory genes such as Arg1 during M1-to-M2 macrophage polarization [15, 84]
