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Current therapeutic approaches for ovarian aging include antioxidant supplementation, stem cell-based therapies, and hormonal or growth factor support [95]
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doi: 10.1038/sj.ejcn.1602300 8 AquilanoK.BaldelliS.CirioloM
Bashar T, Akhter N
In addition to this, treatment of A549 and H3122 cells with SAG caused an increase in intracellular Fe 2+ concentration, ROS levels and MDA content as well as a decrease in GSH content, which was thus shown to also trigger ferroptosis in lung cancer [217]
ROS are inextricably linked to the cellular oxidation of fuels, when liberated electrons (reducing equivalents) modify the balance of reduced and oxidized pairs of electron acceptors such as NADH/NAD + and NADPH/NADP +
