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This is supported by metabolomic profiling studies that have identified complex lipid species and amino acid analogues associated with the response to weight loss interventions

Side effects In terms of cardiovascular side effects, phentermine can cause increased blood pressure, an elevated heart rate, and palpitations

it can take years for the affects to manifest as symptoms

Signs of kidney problems may include changes in urination patterns, swelling in the legs or feet, or unusual fatigue

Vitamin B12 injection is a newer treatment modality for the management of obesity and involves intramuscular administration of vitamin B12 solution using a syringe to promote weight loss in obese patients

Beyond Month 6: Maintenance Most patients continue at 2.4 milligrams weekly through month 12, when full clinical trial endpoints are typically reached