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Its kind of this melancholic melody

Marked elevations in liver function test results (e.g., AST [SGOT] and ALT [SGPT]), occurred on 2 occasions following administration of high doses (total doses: 106 and 250 g over 3-4 days) of acetylcysteine rectally and via nasogastric tube in a 3-year-old boy with cystic fibrosis

doi: 10.1007/s00774-012-0378-9

Over the years, probe design evolved to include more selective and photostable fluorophores, near-infrared and two-photon probes for deep-tissue imaging and organelle-targeted sensors directed to mitochondria, Golgi, nucleus or ER

Davioud-Charvet E, Delarue S, Biot C, Schwobel B, Boehme CC, Mussigbrodt A, Maes L, Sergheraert C, Grellier P, Schirmer RH and Becker K

1995;62(6 Suppl):1315S-1321S