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the first full characterization appeared in 1998

What if my doctor refuses to order the tests I need

doi: 10.1111/jpi.12052 371 HolickCNGiovannucciELRosnerBStampferMJMichaudDS

The general principle described in clinical teaching is to establish a baseline, recheck IGF-1 after the early weeks of any protocol, keep it within an age-appropriate reference range rather than pushing it into supraphysiologic territory, and monitor fasting glucose in at-risk patients

Braz J Med Biol Res 2012

This is like when reviews on dairy conclude milk does more good than harm in part because of all the calcium, despite links to diseases like Parkinsons and prostate canceras if the only source of calcium on the planet were dairy