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10.1016/j.jep.2023.116729 168 WangX.XiaoA.YangY.ZhaoY.WangC

Though systematic absorption of topically applied retinoids, such as retinol and tretinoin, is low, doctors recommend avoiding them while pregnant and nursing

Vitamin B12 injections are typically used to treat a deficiency in people who are unable to absorb adequate amounts of B12

The demonstrated safety, biocompatibility, and anti-aging benefits of HC make it a valuable ingredient for addressing common concerns such as dryness, laxity, and wrinkles, further solidifying its position in the skincare and dietary supplement markets [10]

As such, there is no agreed recommended safe dosage, and some side effects might occur depending on individual response