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For immune-related disorders, psoriatic patients showed increased activities of antioxidant defenses in the circulating granulocytes and the affected epidermis with the combined supplementation of CoQ 10 , vitamin E, and selenium [208]

The high density of mitochondria provides numerous targets for copper binding to lipoylated TCA cycle enzymes, directly disrupting the energy supply vital for contraction [75]

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an ostomy refers to an opening of the bowel brought to the skin to allow egress of intestinal fluids through the os, but -ostomy may also refer to tubes placed in GI organs that cannot reach the skin (i.e., duodenostomy, gastrostomy)