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Fibroblast activation and ECM remodeling Biomolecules (2018) Anti-Inflammatory Inflammation Modulation Bioinformatic analyses show GHK-Cu downregulates gene networks associated with inflammation and oxidative stress, potentially explaining its tissue repair properties

Cross-Reactivity Human, Mouse Purification Antigen-specific affinity chromatography followed by Protein A affinity chromatography Immunogen Recombinant Glutathione Peroxidase 1 (GPX1) corresdonding to Gly48~Pro201 with N-terminal His Tag Isotype IgG Application Notes Western blotting: 0.01-2 g/mL,Immunohistochemistry: 5-20 g/mL,Immunocytochemistry: 5-20 g/mL,Optimal working dilutions must be determined by end user

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Studies have shown that oxidative stress upregulates the expression of intercellular adhesion molecule 1(ICAM-1) in epithelial cells through an IL-6/AKT/ST4T3/NF-KB dependent pathway, and its upregulation is closely related to pro-inflammatory cytokines such as IL-6, IL-1, and TNF- (44)