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Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen

It is possible these variants could also impact cancer risk

To demonstrate specificity of the effect, we sought to rescue the decreased mEPSC frequency by pretreating with pyroglutamate (PGA), the precursor of glutamate that is synthesized downstream of GGT, which is blocked by acivicin (Fig

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full-length hGH on lipolytic activity IGF-1 independence and selective metabolic effects Cartilage regeneration and joint biology in preclinical models
