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However, numerous studies have demonstrated physiological differences between mouse strains and even between the same strain bred at different commercial vendors and for this reason, it is very important to be informed on the strain and substrains of choice (Mekada et al., 2009, Bryant, 2011, Fontaine and Davis, 2016)

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Semaglutide has been shown to cause dose-dependent and treatment duration-dependent malignant thyroid C-cell tumors at clinically relevant exposures in both genders of rats and mice

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