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Furthermore, PCR reactions were performed using primers designed to bind up- or down-stream of the gene of interest in combination with primers designed to bind inside the antibiotic resistance maker genes
These risks become especially relevant during repeated or long-term administration, which is often necessary for CNS-targeted therapies
10.1016/j.ceb.2015.02.003 89 ShuklaP
Furthermore, anesthesia disrupts mitochondrial dynamics by upregulating fission protein Drp1 while suppressing fusion mechanisms, resulting in fragmented, inefficient mitochondrial networks incapable of meeting neuronal energy demands (24)
10.1155/2019/5256460 [DOI] [PMC free article] [PubMed] [Google Scholar] 77.Oda E, Aoyagi R, Aizawa Y
