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Together, these results support a model in which venous-derived (Aplnr + ) ECs give rise to Esm1 + cells, which, in turn, differentiate into Bmx+ arterial ECs and thereby progressively contribute to the mesenteric arterial network (Supplementary Fig

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The structure of ZnT proteins is inferred from the Escherichia coli homologs of YiiP, 104 which have six TM helices (TM helices I-VI) and their N- and C-termini situated on the cytoplasmic side