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67 Copy number gain is a prominent feature in myeloma and other cancers, and hypoxiainduced 1q21 copy number gain or amplification (1q21+) has been reported in breast cancer cells

There was no significant difference in concentrations between the treatment groups

the 50 mg vial gives 20 doses at 2.5 mg

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The DSMB members have prepared a charter and decided the study stopping rules, and will review the SAEs and AEs reported in the study periodically