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doi: 10.3389/fimmu.2025.1534926 Received 26 November 2024 Accepted 17 January 2025 Published 04 February 2025 Volume 16 - 2025 Edited by Yue Liu, Boston Childrens Hospital and Harvard Medical School, United States Reviewed by Jin-Ming Zhang, University of Texas Health Science Center at Houston, United States Zurong Wan, Cornell University, United States Updates Copyright 2025 Zhao, Li, Zhang, Wang, Deng, Xu, Jin, Zuo, Xun, Luo, Yang, Qi and Fu

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Future research ought to concentrate on the translation of targeted delivery technologies and the optimization of combination therapies to promote the practical implementation of DNase I in the treatment of LN