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Since the microbiome contributes to systemic immunity and can metabolise certain drugs, this may represent an indirect mechanism affecting both host susceptibility to TB and the bioavailability of orally administered anti-TB agents (Leite et al., 2022

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doi: 10.1002/j.2040-4603.2019.tb00055.x 157 WensveenFMValentiSestanMTurk WensveenTPoliB

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