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Importantly, although the relationship between Notch and Nrf2 is controversial, the authors suggested that the toxic effects exerted by DEHP in the testis were due to a pro-oxidant mechanism that activates the Nrf2-mediated Notch1 pathway [156]
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The major detoxification pathway of 4HNE involves GSTs 16
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Bacterial infections in patients requiring admission for an acute exacerbation of COPD
Therefore, the mitochondrial quality control system plays a critical role in the onset and progression of neurodegenerative diseases
