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First-line treatment for postherpetic neuralgia usually includes medications that reduce nerve excitability and topical treatments that calm the affected skin

S2CID 20350330

NAD+ is a critical coenzyme involved in hundreds of enzymatic reactions including glycolysis, the citric acid cycle, and oxidative phosphorylation, as well as serving as a substrate for NAD+-consuming enzymes including sirtuins, PARPs, and CD38

Mechanism of Action (as reported in preclinical literature)

Treatment sessions are usually spaced one week apart

Most research shows sustained effects throughout treatment periods without apparent tolerance development