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Fluorescence microscopy was performed using the Cytation 5 Imaging Multi-Mode Reader (BioTek, Agilent, Switzerland) with Gen5 software
It is conceivable that neuronal RNA oxidation occurs before significant A or tau pathology in AD
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Additionally, two small studies in participants presenting with antiretroviral-induced neuropathy found significant reduction in subjects' mean pain intensity with oral ALCAR (1-3 g/day) for 4 to 24 weeks, but no effect on objective neurophysiological parameters was found (82, 83)
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